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Safety Warning

Beware Before You Use Tribulus Terrestris (Gokshura)! 🌿⚠️

Published on December 18, 2024 • 6 min read

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Critical Safety Information

Tribulus terrestris is a small flowering plant traditionally used in Ayurvedic and Chinese medicine to enhance libido, stamina, and strength. It contains active compounds like saponins, especially protodioscin, believed to support testosterone levels and athletic performance.

However, scientific evidence for its effectiveness is still limited, and it can interact dangerously with prescription medications.

Beware Before You Use Tribulus/Gokshura - Safety warning showing Tribulus terrestris plant with flowers and spiny fruits

Cross-Interactivity with Prescription Drugs

💧

Diuretics

Tribulus may enhance the effects of diuretic drugs, potentially increasing the risk of dehydration or electrolyte imbalance.

⚠️ Monitor hydration levels and electrolyte balance closely

💉

Antidiabetic Drugs

Tribulus may lower blood sugar, so combined use with diabetes medications could cause hypoglycemia.

⚠️ Monitor blood glucose levels frequently and adjust medication as needed

❤️

Antihypertensive Drugs

Tribulus has blood pressure-lowering effects and may add to the effects of ACE inhibitors or other blood pressure medications, risking hypotension.

⚠️ Regular blood pressure monitoring essential

🧠

Lithium

Tribulus may reduce the body's ability to clear lithium, raising lithium levels and risk of toxicity.

🚫 Avoid concurrent use - consult psychiatrist immediately

Furthermore...

🩸 Clopidogrel and Blood Thinners

Case reports suggest a possible increased risk of blood clots when used with clopidogrel, though causality is unclear.

💊 Statins and CYP3A4 Substrates

Tribulus may inhibit CYP3A4, affecting the metabolism of drugs like atorvastatin and increasing the risk of side effects such as rhabdomyolysis.

🔄 P-glycoprotein Substrates

Tribulus may inhibit P-gp, potentially increasing levels of drugs transported by this protein.

Always Remember

Herbal medicines are a gateway to natural healing and a less harmful approach to health restoration. However, they should be consumed under guided intervention, making it essential to know the risks of consuming herbs that can cross-interact with your present medical regime.

🚨 When to Seek Medical Help

Stop using Tribulus and contact your healthcare provider immediately if you experience:

  • Severe hypoglycemia (extremely low blood sugar)
  • Signs of dehydration or electrolyte imbalance
  • Unusual changes in blood pressure
  • Signs of lithium toxicity (confusion, tremors, nausea)
  • Unusual bleeding or clotting
  • Muscle pain or weakness (possible rhabdomyolysis)
📄

Download BBU Guide

Get the complete Beware Before You Use guide for Tribulus as a PDF.

Safety Checklist

Consulted healthcare provider
Checked all medication interactions
Not taking diuretics or blood pressure meds
Not diabetic or on blood sugar medications
Not taking lithium or psychiatric medications
🚨

Medical Emergency?

If experiencing severe reactions, contact emergency services immediately.

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